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children's Diabetes type 2,Why does the fact that you've got it make me more likely to get it?"

Question:
I was chatting to one of my sisters (I have 3) the other day about how I was getting on with my diabetes. I mentioned some statistics I'd read in a book about diabetes, written for a parent concerned about their children's chance of developing type 2. It went something like this:

"If you are a father with type 2 diabetes [ our father has type 2], each of your children has a 5% chance of having diabetes. If one of your children develops diabetes, any other children have a 10% chance of developing it."

I said to my sister, "So you have a one in 10 chance of getting diabetes".

She said, "Why does the fact that you've got it make me more likely to get it?"

I said I had no idea of the reason, but those were the statistics. Anybody got a better answer?

The book also said that having a diabetic father is moe of a risk factor than having a diabetic mother. Any idea why, anyone?




Answer:
You need to revisit your source. The numbers above appear to be a combination of type 1 statistics and incorrect statistics. The child of a type 1 parent has a 5% risk. The child of a type 1 father has a 6.1% risk. The child of type 1 mother who was younger than 25 at the birth of the child has a 3.6%, older than 25 a 1.1% risk. If you have a type 1 sibling, you have a 5% risk.

The risks of type 2 are much harder to charaterize since type 2 is even more a collection of a variety of conditions with a common clinical profile. In general, if you live to 70, you have a 11% risk of developing type 2 independent of family history.

As to your question, I haven't seen any indication that having both a sibling and parent with diabetes, of either type, imposes a higher risk than only having one or the other. If your book does indeed say that, would you post its title and the references it cites, if any.


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