Question:
Whether obesity is a reason/cause of getting Type 2 diabetes OR Type 2
diabetes with deficient action of insulin is the cause/reson of making
a person obese(central obesity)--may be due to conversion of excess
glucose into fats?
How a type2 patient can get deficient secretion of insulin in early
stages? Can excess BG level cause low secretion of insulin?
Answer:
1. "Excess bG" comes late in the Type 2 Diabetes Progression. Much of
the damage has occurred before the high bG shows up. The high bG start to
show up when about half of the Type 2 Diabetic's beta cells are
non-functional. (See UKPDS, DCCP)
2. High Insulin Resistance is associated with the abdominal fat (visceral
fat) inside the abdominal wall, i.e. Omental Fat. You can't see if
easily, you can't even measure it easily The docs estimate Omental Fat
levels via NMR scans and the like.
Quite a few folks think that high Insulin Resistance encourages general fat
deposition. If so, that suggests that a genetic tendency toward Omental
Fat production can increase Insulin Resistance which in turn encourages
overall fat deposition leading to more visible obesity.